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Malaria and Emerging Parasitosis

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Referencia e Investigación en Helmintos

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Predominance of CXCR4 tropism in HIV-1 CRF14_BG strains from newly diagnosed infections.

Pérez-Álvarez L, Delgado E, Vega Y, Montero V, Cuevas T, Fernández-García A, García-Riart B, Pérez-Castro S, Rodríguez-Real R, López-Álvarez MJ, Fernández-Rodríguez R, Lezaun MJ, Ordóñez P, Ramos C, Bereciartua E, Calleja S, Sánchez-García AM, Thomson MM. Predominance of CXCR4 tropism in HIV-1 CRF14_BG strains from newly diagnosed infections. J Antimicrob Chemother. 2014; 69:246-253.

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Molecular epidemiology, phylogeny, and phylodynamics of CRF63_02A1, a recently originated HIV-1 circulating recombinant form spreading in Siberia.

Shcherbakova NS, Shalamova LA, Delgado E, Fernández-García A, Vega Y, Karpenko LI, Ilyichev AA, Sokolov YV, Shcherbakov DN, Pérez-Álvarez L, Thomson MM. Molecular epidemiology, phylogeny, and phylodynamics of CRF63_02A1, a recently originated HIV-1 circulating recombinant form spreading in Siberia. AIDS Res Hum Retroviruses. 2014; 30:912-919.

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Epidemiological surveillance of HIV-1 transmitted drug resistance in Spain in 2004-2012: relevance of transmission clusters in the propagation of resistance mutations.

Vega Y, Delgado E, Fernández-García A, Cuevas MT, Thomson MM, Montero V, Sánchez M, Sánchez AM, Pérez-Álvarez L; Spanish Group for the Study of New HIV-1 Diagnoses in Galicia and Basque Country. Epidemiological surveillance of HIV-1 transmitted drug resistance in Spain in 2004-2012: relevance of transmission clusters in the propagation of resistance mutations. PLoS One. 2015; 10:e0125699.

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Phylogeny and phylogeography of a recent HIV-1 subtype F outbreak among men who have sex with men in Spain deriving from a cluster with a wide geographic circulation in Western Europe.

Delgado E, Cuevas MT, Domínguez F, Vega Y, Cabello M, Fernández-García A, Pérez-Losada M, Castro MÁ, Montero V, Sánchez M, Mariño A, Álvarez H, Ordóñez P, Ocampo A, Miralles C, Pérez-Castro S, López-Álvarez MJ, Rodríguez R, Trigo M, Diz-Arén J, Hinojosa C, Bachiller P, Hernáez-Crespo S, Cisterna R, Garduño E, Pérez-Álvarez L, Thomson MM. Phylogeny and phylogeography of a recent HIV-1 subtype F outbreak among men who have sex with men in Spain deriving from a cluster with a wide geographic circulation in Western Europe. PLoS One. 2015; 10:e0143325.

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Información adicional

Despite progress, parasitic diseases remain a major challenge for humans. Its rapid and accurate detection, as well as the identification of specific genes related to virulence and/or resistance to treatments, is a necessity for management and planning control strategies. 

The main objective of the group is to carry out quality, competitive and innovative research, to acquire, disseminate and apply in clinical parasitology with the ultimate goal of improving and innovating in the diagnoses, therapies and control of parasitic diseases. This general objective is implemented through external projects and collaborations with different funding sources:

- Characterization of submicroscopic malaria. National Hospital Network. (FIS-ISCIII).
- Design, optimization and validation of advanced diagnostic methods for the detection of blood parasites (Retos-MICINN).
- Control of onchocerciasis in Equatorial Guinea. CNMTrop-ISCIII (Task Force, USA).
- Characterization and control of Mansonellosis and Onchocerciasis in the Amazon region in Brazil. FIOCRUZ from Amazonas, Brazil. (Cpnqt-Brazil).
- Plasmodium knowlesi and its implication as the fifth species of human malaria. MRC, Malaysia.
- Intestinal parasitosis in Egypt from Cryptosporidium (protozoan) to Capillaria (Nematode). Cairo University and Al-Azhar University, Egypt. (MHESR, AECID).

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