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Malaria and Emerging Parasitosis

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Identification of an HIV-1 BG intersubtype recombinant form (CRF73_BG), partially related to CRF14_BG, which Is circulating in Portugal and Spain.

Fernández-García A, Delgado E, Cuevas MT, Vega Y, Montero V, Sánchez M, Carrera C, López-Álvarez MJ, Miralles C, Pérez-Castro S, Cilla G, Hinojosa C, Pérez-Álvarez L, Thomson MM. Identification of an HIV-1 BG intersubtype recombinant form (CRF73_BG), partially related to CRF14_BG, which Is circulating in Portugal and Spain. PLoS One. 2016; 11:e0148549.

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Sequence analysis of in vivo-expressed HIV-1 spliced RNAs reveals the usage of new and unusual splice sites by viruses of different subtypes

Vega Y, Delgado E, de la Barrera J, Carrera C, Zaballos Á, Cuesta I, Mariño A, Ocampo A, Miralles C, Pérez-Castro S, Álvarez H, López-Miragaya I, García-Bodas E, Díez-Fuertes F, Thomson MM. Sequence analysis of in vivo-expressed HIV-1 spliced RNAs reveals the usage of new and unusual splice sites by viruses of different subtypes. PLoS One. 2016; 11:e0158525.

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HIV-1 genetic diversity in recently diagnosed infections in Moscow: predominance of AFSU, frequent branching in clusters, and circulation of the Iberian subtype G variant.

Karamov E, Epremyan K, Siniavin A, Zhernov Y, Cuevas MT, Delgado E, Sánchez-Martínez M, Carrera C, Kornilaeva G, Turgiev A, Bacqué J, Pérez-Álvarez L, Thomson MM. HIV-1 genetic diversity in recently diagnosed infections in Moscow: predominance of AFSU, frequent branching in clusters, and circulation of the Iberian subtype G variant. AIDS Res Hum Retroviruses. 2018; 34:629-634.

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Bayesian phylogeographic analyses clarify the origin of the HIV-1 subtype A variant circulating in former Soviet Union's countries.

Díez-Fuertes F, Cabello M, Thomson MM. Bayesian phylogeographic analyses clarify the origin of the HIV-1 subtype A variant circulating in former Soviet Union's countries. Infect Genet Evol. 2015; 33:197-205.

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Información adicional

Despite progress, parasitic diseases remain a major challenge for humans. Its rapid and accurate detection, as well as the identification of specific genes related to virulence and/or resistance to treatments, is a necessity for management and planning control strategies. 

The main objective of the group is to carry out quality, competitive and innovative research, to acquire, disseminate and apply in clinical parasitology with the ultimate goal of improving and innovating in the diagnoses, therapies and control of parasitic diseases. This general objective is implemented through external projects and collaborations with different funding sources:

- Characterization of submicroscopic malaria. National Hospital Network. (FIS-ISCIII).
- Design, optimization and validation of advanced diagnostic methods for the detection of blood parasites (Retos-MICINN).
- Control of onchocerciasis in Equatorial Guinea. CNMTrop-ISCIII (Task Force, USA).
- Characterization and control of Mansonellosis and Onchocerciasis in the Amazon region in Brazil. FIOCRUZ from Amazonas, Brazil. (Cpnqt-Brazil).
- Plasmodium knowlesi and its implication as the fifth species of human malaria. MRC, Malaysia.
- Intestinal parasitosis in Egypt from Cryptosporidium (protozoan) to Capillaria (Nematode). Cairo University and Al-Azhar University, Egypt. (MHESR, AECID).

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