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Investigation
Human viruses of the herpesviridae family
Publications
Transmission clusters, predominantly associated with men who have sex with men, play a main role in the propagation of HIV-1 in Northern Spain (2013-2018).
Gil H, Delgado E, Benito S, Georgalis L, Montero V, Sánchez M, Cañada-García JE, García-Bodas E, Diaz A, Thomson MM and Spanish group of the study of new HIV diagnoses. Front Microbiol. 2022. 13:782609
PUBMED DOIPotent Induction of Envelope-Specific Antibody Responses by Virus-Like Particle Immunogens Based on HIV-1 Envelopes from Patients with Early Broadly Neutralizing Responses
Beltran-Pavez C, Bontjer I, Gonzalez N, Pernas M, Merino-Mansilla A, Olvera A, Miro JM, Brander C, Alcami J, Sanders RW, Sanchez-Merino V, Yuste E; J Virol. 2022 Jan 12;96(1):e0134321.
PUBMED DOIAdditional Information
Our group is interested in infections caused by the 8 known human herpes, which are very important etiological agents due to the high rates of infection, as well as their morbidity and mortality, especially in situations in which the immune system is immature (pediatric disease), senescent (pathologies in advanced age) or immunocompromised (transplanted).
They form a very heterogeneous group, but once the infection occurs, it persists for life through its latency phases. The pathogenicity of alpha- and beta-herpesviruses is related to primary infection and its recurrences, but in gamma-herpesviruses their main pathogenicity lies in their ability to produce tumors.
The main objective of the group is to respond to the medical problems caused by these infections from a multidisciplinary point of view, which includes virological, immunological and molecular aspects.
At present, the group's specific research objectives focus mainly on two topics:
Pathogenicity markers in congenital cytomegalovirus disease that modulate the immune system during infection and
Molecular characterization of the varicella zoster virus in cases of vaccine failure. The group's IP is part as a promoter partner of Spin-off: Virnóstica-ISCIII
Our group is interested in infections caused by the 8 known human herpes, which are very important etiological agents due to the high rates of infection, as well as their morbidity and mortality, especially in situations in which the immune system is immature (pediatric disease), senescent (pathologies in advanced age) or immunocompromised (transplanted).
They form a very heterogeneous group, but once the infection occurs, it persists for life through its latency phases. The pathogenicity of alpha- and beta-herpesviruses is related to primary infection and its recurrences, but in gamma-herpesviruses their main pathogenicity lies in their ability to produce tumors.
The main objective of the group is to respond to the medical problems caused by these infections from a multidisciplinary point of view, which includes virological, immunological and molecular aspects.
At present, the group's specific research objectives focus mainly on two topics:
Pathogenicity markers in congenital cytomegalovirus disease that modulate the immune system during infection and
Molecular characterization of the varicella zoster virus in cases of vaccine failure. The group's IP is part as a promoter partner of Spin-off: Virnóstica-ISCIII